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Question: What detection or calculation method is more scientific for signal detection when the data pool used for signal detection is small?
Answer: A small data pool can be used for signal detection using qualitative or simple quantitative methods. Medical alert professionals manually review individual case reports and summarize reports to identify 'suspicious reports', or conduct summary analysis using case numbers, reporting rates, and corrected reporting rates to identify signals worth further evaluation. Reference: Comparative Study on Drug Signal Detection and Evaluation at Home and Abroad, China Pharmacovigilance Vol.19, No.11